Fry has been a delivery boy for 1000 plus years. He is well known for his terrible work ethic, stupidity, and boyish charm.
Bender is a manbot that lives life in the fast lane. He relishes the finer things such as a nice drink, a classy cigar and killing all humans.
Leela is the hard-hitting one-eyed captain of the Planet Express ship. She has a complicated and emotional past full of failed love and mutants.
At 160 years old Professor Farnsworth is a renowned and senile inventor. His inventions have saved and almost destroyed the earth many times.
Dr. Zoidberg is a failed comedian turned doctor. He is a poor, lonely, and foul smelling sea-monster alien with a good heart and a good ink gland.
Amy's parents Leo and Inez Wong own half of Mars. Most of her success stems from her good looks and being mega-rich.
Hermes Conrad is the Planet Express Bureaucrat. He hails from Jamaica and competed on their Olympic limbo team.
Zapp Brannigan is the velour wearing Commander of the Nimbus, a Democratic Order of Planets starship. He's as vain and dumb as he thinks he is sexy.
Kiff is Lieutenant to Zapp Brannigan. He is a spineless green alien. In fact, he has no bones at all but is supported by a system of fluid-filled bladders.
Nibbler is a male Niblonian, a noble race that eats anything alive and excretes starship fuel. He is very noble and also very cute.
Scruffy's the janitor.
Mom owns one of the biggest corporations in the universe. To most she seems to be a sweet old lady, but those close to her know she's evil.